Here's this years screen reader survey results from Webaim. Apart from accessibility issues it contains a lot of good best practices and correct methods of presenting content.

 

Survey results: http://webaim.org/projects/screenreadersurvey2/

Blog post: http://webaim.org/blog/screen-reader-user-survey-results/

That's great stuff and so well presented. I'll be reading that in depth when I get the time, but the way it was laid-out was drawing me in and made for interesting reading.

I hope designers are taking this seriously.

I was already aware of these two but they caught my eye...

 

50.8% navigate using HTML headings on the page

 

Using a photo of a smiling lady on the page the respondants preferred ALT attribute was...

 

57.1% preferred "Photo of smiling lady"

20.2% preferred "Smiling lady"

 

note the lack of keyword stuffing