A while back I was looking for a way to filter a list of images in a custom gallery without reloading anything on the page. Of the rather limited few I did find,
Quicksand seemed to be the best, but it was a nightmare to configure and I couldn't get it to work without pulling out half my hair...
Anyway, I just found one that had somehow eluded all my previous searches, but it's by far the best looking real-time category filter plugin I've ever seen.

Have a look at
Isotope, written by David DeSandro. And while you're there, don't miss the Masonry plugin (link on the Isotope page).
My favourite part is that it uses CSS3 transitions and GPU acceleration when available for better performance, and with a simplified and integrated miniModernizr script, it safely falls back to JS for 'older browsers'.

I found that somewhat amusing.